Subtitle: Pioneering a New Era in Cell Counting Technology
Introduction:
Cell counting has been a cornerstone in scientific and medical research, providing critical insights into biological processes and cell viability. The journey began with Louis-Charles Malassez's invention of the hemocytometer, a groundbreaking device that laid the foundation for cell counting. However, as technology advanced, NanoEntek emerged as a key player, revolutionizing the process and simplifying cell counting through a series of innovative products.
The Origin of Cell Counting and Development: Hemocytometer
Louis-Charles Malassez's hemocytometer marked the inception of cell counting, offering a precise method for counting blood cells. The Neubauer counting chamber became a standard tool in laboratories. This traditional method, while effective, presented inconveniences that inspired NanoEntek to pioneer advancements.
NanoEntek’s Continuous innovation towards Cell counting
1) NanoEntek’s innovation in Simplifying Cell Counting: C-chip
In response to the inconvenience associated with traditional glass slide hemocytometer, NanoEntek invented ‘C-chip’ - a disposable plastic hemocytometer. The C-chip eliminated the need for washing and cover slips, streamlining the cell counting process while maintaining accuracy. This innovation was a pivotal step in simplifying and modernizing cell counting techniques.
2) NanoEntek’s Evolution in Automated Cell Counting: Countess™
NanoEntek's commitment to innovation continued with the development of the Countess™, an automated cell counter exclusively supplied to 'Life Technologies.' With over 10,000 devices sold globally, Countess™ marked the initiation of a global marketplace for automated cell counting. Recognized as an ODM product, it paved the way for more advanced automated cell counting technologies.
3) NanoEntek’s Innovation Continues: EVE™, EVE™ Plus
Building on the success of the Countess™, NanoEntek introduced faster and more accurate automated cell counters, namely 'EVE™' and 'EVE™ Plus.' These devices not only expedited the counting process but also incorporated automated image analysis, enhancing the assessment of cell viability. The presentation of data in graphical formats further improved user convenience, allowing for more comprehensive and insightful analysis.
NanoEntek’s Product Line-up for Cell Counting
1) Automated Cell counter
NanoEntek's product lineup for cell counting includes the C-chip (2ch/4ch), a disposable hemocytometer known for its high accuracy and time-saving features. EVE™ Plus stands out as one of the fastest cell counters, capable of counting cells within 1 second. For precise cell counting, ADAM™-MC2 utilizes PI staining technology. Notably, ADAM™-CellT meets the regulatory standards of 21CFR Part 11, making it suitable for use in cGMP production environments.
2) High-throughput automated cell counter
(1) EVE™ HT
EVE™ HT is an automated cell counter that uses trypan blue for high-throughput measurements.
In less than 3 minutes, it can accurately measure up to 48 samples, making it an efficient solution for busy laboratories or industries. The efficiency is maximized through the use of a disposable 48 channel plate. For those in regulated environments, EVE™ HT offers an optional 21CFR Part11 compliance, ensuring data integrity and security.
(2) EVE™ HT FL
EVE™ HT FL is a high-throughput dual fluorescence cell counter.
Equipped with a bright field and two fluorescence channels, namely AO and DAPI, EVE™ HT FL exceeds in speed and accuracy. In fact, its accuracy is evidenced with the R squared value of 0.99 it shows when compared to a flow cytometer. EVE™ HT FL can accurately measure up to 48 samples in less than 3 minutes, making it an efficient solution for busy laboratories or industries. The efficiency is maximized through the use of a disposable 48-channel plate.
Remarkably, EVE™ HT FL only requires 20µL of sample per each measurement, which allows users to substantially reduce sample consumption by up to 25 times less than the competing instruments. This not only promotes efficient usage of the samples, but also let users to preserve their precious samples for additional evaluations or experiments.
EVE™ HT FL offers an outstanding high-throughput cell counting method suitable for research and development in bio-processing and cell therapies. Its combination of speed, accuracy, and sample efficiency makes it a valuable tool in various scientific applications.
NanoEntek’s Innovation
For the past 20 years, NanoEntek has consistently led in innovation, introducing creative and groundbreaking products. Our dedication to sharing inventive ideas for the continuous development of our world is unwavering. Through a relentless pursuit of creativity, we aim to make meaningful strides in enhancing our global community.
